β-lactam allergy in children

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Proven Non-β-Lactam Antibiotic Allergy in Children.

BACKGROUND Parallel to the increasing use of non-β-lactam (NBL) antibiotics, allergic reactions to this drug group seem to increase. Data about NBL antibiotic hypersensitivity in children are limited. The aim of this study is to evaluate characteristic reactions to NBL antibiotics in children. METHOD Patients with suspected NBL allergy were assessed between 2011 and 2015. Characteristics of t...

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β-lactam allergy: clinical implications and costs

BACKGROUND β-lactam allergy is the most commonly reported medication allergy and it remains a key issue in antibiotic prescribing. A detailed and accurate history taking play a key role in preventing potentially serious clinical incidents and it may contribute in reducing costs. METHODS Data were collected for patients with a documented penicillin allergy on their drug chart during a six mont...

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Occupational allergy to β-lactam antibiotics

Background Contact urticaria in atopic patients was described by Hannuksela [1], among others, in 1980. It generally appears within 30 min of allergen contact and, in the majority of cases, is restricted to the areas of contact; however, local spread and generalized urticaria in the sense of anaphylaxis are seen. Allergic rhinoconjunctivitis and asthma may also subsequently occur [2]. Von Krogh...

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Allergy to b-Lactam Antibiotics in Children

Background. Skin tests with soluble b-lactams can be used to diagnose immediate and delayed hypersensitivity (HS) reactions to b-lactam antibiotics. Very few studies have been performed with children with suspected b-lactam allergy. In these studies, immediate HS to b-lactams was diagnosed by skin tests in 4.9% to 40% of children. The diagnostic and predictive values of immediate responses in s...

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Skin testing with β-lactam antibiotics for diagnosis of β-lactam hypersensitivity in children.

OBJECTIVE Skin testing with penicilloyl-polylysine (PPL) and a minor determinant mixture (MDM) were previously recommended for evaluating β-lactam hypersensitivity. However, PPL and MDM have not been commercially available. This study was to determine the negative predictive value (NPV) of skin testing with β-lactam antibiotics for the diagnosis of β-lactam hypersensitivity. METHOD Patients a...

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ژورنال

عنوان ژورنال: SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital

سال: 2021

ISSN: 1302-7123

DOI: 10.14744/semb.2021.24434